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A piano is a musical instrument that produces sound by striking a hammer when a key is pressed, while a synthesizer is an electronic instrument that can generate multiple sounds, which can mimic other instruments like a piano, violin, flute, and many more. Synthesizers also allow the user to modify the sounds by adjusting various parameters, such as frequency, attack, decay, sustain, and release (ADSR), envelope, filter, and modulation. In contrast, a piano has a fixed sound for each key.