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The best vocal synth can be subjective to your needs and preferences, but some popular ones include Virus TI2, Tyrox 3, and Serum. Virus TI2 offers a large sound library and a warm, analog-style sound. Tyrox 3 features a hybrid engine for granular and sample-based resynthesis, allowing a wide variety of sounds. Serum is known for its high-quality resampling and wavetable oscillators, perfect for electronic music.